Mouse Pxk Antibody (Center) [APR17442G]

Mouse Pxk Antibody (Center) [APR17442G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M

Specificity: This Mouse Pxk antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 164-193 amino acids from the Central region of mouse Pxk.

Cellular Localisation: Cytoplasm. Cell membrane; Peripheral membrane protein. Note=Also associates with the plasma membrane

Molecular Weight: 65231

Clone: Polyclonal

Gene Name: Pxk {ECO:0000312|MGI:MGI:1289230}

Gene ID: 218699

Function: Binds to and modulates brain Na, K-ATPase subunits ATP1B1 and ATP1B3 and may thereby participate in the regulation of electrical excitability and synaptic transmission. May not display kinase activity.

Summary: Tissue Location: Isoform 1 is present in all tissues examined. Isoform 2 is found in all tissues except skeletal muscle and very low levels in spleen. Both isoforms are widely expressed throughout the nervous system however levels of isoform 2 are higher in purified hippocampal and cortical neurons whereas glial cells express more isoform 1 than isoform 2.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, IHC-P

Dilution: WB--1:1000 IHC-P--1:100~500

Synonyms: PX domain-containing protein kinase-like protein, Modulator of Na, K-ATPase, MONaKA, Pxk {ECO:0000312|MGI:MGI:1289230}