Description
GSTM1 is a glutathione S-transferase that belongs to the mu class. This enzyme acts by catalyzing the reaction of glutathione with an acceptor molecule to form an S-substituted glutathione (S=sulfur). The reactions utilizing glutathione contribute the transformation of a wide variety of electrophiles, including reactive products of lipid, protein, carcinogens, therapeutic drugs, environmental toxins, and products of oxidative stress.
6349 | Mouse Recombinant GSTM 1 DataSheet
Biomolecule/Target: N/A
Synonyms: Mouse Recombinant GSTM 1
Alternates names: Glutathione S-transferase Mu 1, GST class-mu1, GST 1-1, pmGT10.
Taglines: Plays a role in detoxification of electrophilic compounds
NCBI Gene ID #: 25542
NCBI Gene Symbol: CCL3
Gene Source: Mouse
Accession #: P50229
Recombinant: Yes
Source: E. Coli
Purity by SDS-PAGEs: 95%
Assay: SDS-PAGE
Purity: N/A
Assay #2: N/A
Endotoxin Level: < 1.0 EU per 1 g of protein (determined by LAL method).
Activity (Specifications/test method): N/A
Biological activity: Determined by its ability to chemoattract rat peripheral macrophages using a concentration range of 50-100 ng/ml.
Results: N/A
Binding Capacity: N/A
Unit Definition: Specific activity is defined as the amount of enzyme that conjugates 1.0 µ mole of 1-chloro-2, 4-dinitrobenzene (CDNB) with reduced glutathione per minute at pH 6.5 at 25°C.
Molecular Weight: 25.9 kDa
Concentration: 1 mg/ml
Appearance: Liquid
Physical form description: 1 mg/ml solution in PBS (pH 7.4) containing 5 mM Glutathione
Reconstitution Instructions: Reconstitute in HO to a concentration of 0.1-1 mg/ml. This solution can then be diluted into other aqueous buffers or stored at 4°C for 1 week or 20°C for future use.
Amino acid sequence: N/A