LBD
Mouse Scyl2 Antibody (Center) [APR17445G]
- SKU:
- LBD-APR17445G
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Description
Mouse Scyl2 Antibody (Center) [APR17445G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H, M
Specificity: This Mouse Scyl2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 585-613 amino acids from the Central region of mouse Scyl2.
Cellular Localisation: Cytoplasmic vesicle, clathrin-coated vesicle {ECO:0000250|UniProtKB:Q6P3W7}. Golgi apparatus, trans-Golgi network membrane {ECO:0000250|UniProtKB:Q6P3W7}. Endosome membrane {ECO:0000250|UniProtKB:Q6P3W7}. Note=Colocalizes to the trans-Golgi network (TGN) and to endosomal membranes with clathrin, transferrin and plasma membrane adapter AP1 and AP3 complexes {ECO:0000250|UniProtKB:Q6P3W7}
Molecular Weight: 103317
Clone: Polyclonal
Gene Name: Scyl2 {ECO:0000312|MGI:MGI:1289172}
Gene ID: 213326
Function: Component of the AP2-containing clathrin coat that may regulate clathrin-dependent trafficking at plasma membrane, TGN and endosomal system. A possible serine/threonine-protein kinase toward the beta2-subunit of the plasma membrane adapter complex AP2 and other proteins in presence of poly-L-lysine has not been confirmed (By similarity) . By regulating the expression of excitatory receptors at synapses, plays an essential role in neuronal function and signaling and in brain development (PubMed:26203146) .
Summary: Tissue Location: Ubiquitously expressed.
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB
Dilution: WB--1:1000
Synonyms: SCY1-like protein 2, Coated vesicle-associated kinase of 104 kDa, Scyl2, Cvak104, D10Ertd802e