Mouse Styk1 Antibody (Center) [APR31258G]

Mouse Styk1 Antibody (Center) [APR31258G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This Mouse Styk1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 210-238 amino acids from the Central region of mouse Styk1.

Cellular Localisation: Membrane; Single-pass membrane protein

Molecular Weight: 48121

Clone: Polyclonal

Gene Name: Styk1

Gene ID: 243659

Function: Probable tyrosine protein-kinase, which has strong transforming capabilities on a variety of cell lines including NIH 3T3 fibroblasts and on athymic nude mice. When overexpressed, it can also induce tumor cell invasion as well as metastasis in distant organs. May act by activating both MAP kinase and phosphatidylinositol 3'-kinases (PI3K) pathways.

Summary: Tissue Location: Highly expressed in colon and small intestine. Weakly or not expressed in spleen, skeletal muscle, liver, kidney, heart and brain. Expressed in transformed kidney cell lines (COS-1 and HEK293T) .

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:2000 WB--1:1000

Synonyms: Tyrosine-protein kinase STYK1, Novel oncogene with kinase domain, mNOK, Serine/threonine/tyrosine kinase 1, Styk1, Nok