Description
Moxetumomab Antibody, Monoclonal | 21-866 | Gentaur UK, US & Europe Distribution
Product Type: Primary Antibodies
Category: Primary Antibodies, Monoclonal Antibodies
Research Area: Drug Analogues
Type: Monoclonal
Host Species: N/A
Reactivity Species: N/A
Homology: N/A
Immunology: N/A
Tested Application: N/A
Application Note: N/A
Positive Control 1: N/A
Positive Control 2: N/A
Predicted Molecular Weight: N/A
Isoform: N/A
Purification: >95%
Clonality: Recombinant Monoclonal
Clone: N/A
Isotype: N/A
Conjugate: Unconjugated
Physical State: N/A
Buffer: PBS buffer pH 7.5
Concentration: N/A
Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at +4°C short term (1-2 weeks) . Store at -20 °C 12 months. Store at -80°C long term.
Additional Names: SIGLEC2; SIGLEC-2
Protein Accession: P20273
User Note: For research use only .
Background: B-cell receptor CD22 is also known as Sialic acid-binding Ig-like lectin 2 (Siglec-2), B-lymphocyte cell adhesion molecule (BL-CAM), T-cell surface antigen Leu-14, which belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. CD22 mediates B-cell B-cell interactions, and may be involved in the localization of B-cells in lymphoid tissues. Siglec-2 / CD22 binds sialylated glycoproteins, one of which is CD45. Siglec2 / CD22 plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.
Loading Controls: N/A
Source: CHO cells
Purity: >95%
CAS: N/A
Shipping Condition: N/A