MPG Polyclonal Antibody | E-AB-10980

MPG Polyclonal Antibody | E-AB-10980 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: 3 alkyladenine DNA glycosylase, 3-alkyladenine DNA glycosylase, 3-methyladenine DNA glycosidase, 3MG, AAG, ADPG, Alkyladenine DNA glycosylase, anpg, APNG, CRA36.1, DNA 3 methyladenine glycosylase, DNA-3-methyladenine glycosylase, MDG, Mid1, Mpg, N methylpurine DNA glycosirase, N methylpurine DNA glycosylase, N-methylpurine-DNA glycosylase, PIG11, PIG16, Proliferation inducing protein 11, Proliferation inducing protein 16

Application: WB, IHC, ELISA

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Epigenetics and Nuclear Signaling

Background: Maintenance of DNA sequences is necessary for vertebrates and other life. DNA is under constant stress by a plethora of DNA-damaging agents present in both the environment and within cells. The potentially deleterious effects of DNA lesions in cells are elegantly resolved by sophisticated DNA repair systems, including base excision repair (BER), nucleotide excision repair (NER) and DNA repair methyltransferase (MTase). Methylated bases, such as 3-methyladenine (3MeA) and 7-methylguanine (7MeG) can be formed by agents in the environment and by endogenous cellular processes. Consequently, in the absence of exposure to environmental agents, DNA methylation damage can be incurred on the genomic DNA of normal mammalian cells. DNA N-glycosylases are base excision-repair proteins that locate and cleave damaged bases from DNA as the first step in restoring the sequence.

Concentration: 0.5 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein of human MPG

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:1000-1:5000, IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 32 kDa

Molecular Weight(Observed): N/A