MPI-5a | B2833

MPI-5a is a potent and selective inhibitor of Histone Deacetylase 6 (HDAC6) with an IC₅₀ of 36 nM. It inhibits the acetylation of tubulin in cells with an IC₅₀ value of 210 nM.

MPI-5a is a potent and selective inhibitor of Histone Deacetylase 6 (HDAC6) with an IC₅₀ of 36 nM. It inhibits the acetylation of tubulin in cells with an IC₅₀ value of 210 nM.

B2833 | MPI-5a DataSheet

Alternate Name/Synonyms: HDAC6 inhibitor; N-hydroxy-2-(1-methylpyrrole-2-carbonyl)-3,4-dihydro-1H-isoquinoline-6-carboxamide; N-hydroxy-2-(1-methyl-1H-pyrrole-2-carbonyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamide

Appearance:

Formulation: A solution in acetonitrile

CAS Number: 1259296-46-2

Structure Available?: True

Peptide sequence:

Salt Form: False

Molecular Formula: C₁₆H₁₇N₃O₃

Molecular Weight: 299.32

Cell-Permeable?: True

Purity: ≥95%

Solubilities: ~30 mg/ml in ethanol, DMSO and DMF in 0

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A selective inhibitor of HDAC6

MDL Number:

PubChem CID: 49831258

SMILES: CN1C=CC=C1C(=O)N2CCC3=C(C2)C=CC(=C3)C(=O)NO

InChi: InChI=1S/C16H17N3O3/c1-18-7-2-3-14(18)16(21)19-8-6-11-9-12(15(20)17-22)4-5-13(11)10-19/h2-5,7,9,22H,6,8,10H2,1H3,(H,17,20)

InChi Key: NNQAQGDSGCGFER-UHFFFAOYSA-N