MPP2 Antibody (C-Term) [APR17455G]

MPP2 Antibody (C-Term) [APR17455G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: M

Specificity: This MPP2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 398-419 amino acids from human MPP2.

Cellular Localisation: Cytoplasm, cytoskeleton. Membrane Cell projection, dendrite {ECO:0000250|UniProtKB:Q9WV34}. Cell junction, synapse, postsynaptic density {ECO:0000250|UniProtKB:Q9WV34} Note=Prominently expressed in the postsynaptic densities of dendritic spines, is also detected in dendritic shafts {ECO:0000250|UniProtKB:Q9WV34}

Molecular Weight: 64581

Clone: Polyclonal

Gene Name: MPP2 (HGNC:7220)

Gene ID: 4355

Function: Postsynaptic MAGUK scaffold protein that links CADM1 cell adhesion molecules to core components of the postsynaptic density (By similarity) . In CA1 pyramidal neurons, required for synaptic KCNN2- containing channel function and long-term potentiation expression (By similarity) . Seems to negatively regulate SRC function in epithelial cells (PubMed:19665017) .

Summary: N/A

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:2000

Synonyms: MAGUK p55 subfamily member 2, Discs large homolog 2, Protein MPP2, MPP2, DLG2