MRI1 Antibody | 61-260

MRI1 Antibody | 61-260 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Homology: N/A

Immunogen: This MRI1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 108-141 amino acids from the Central region of human MRI1.

Research Area: Obesity, Signal Transduction

Tested Application: WB

Application: For WB starting dilution is: 1:8000

Specificiy: N/A

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: 39 kDa

Validation: N/A

Isoform: N/A

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Clonality: polyclonal

Clone: N/A

Isotype: Rabbit Ig

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.

Concentration: batch dependent

Storage Condition: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: Methylthioribose-1-phosphate isomerase {ECO:0000255|HAMAP-Rule:MF_03119}, M1Pi {ECO:0000255|HAMAP-Rule:MF_03119}, MTR-1-P isomerase {ECO:0000255|HAMAP-Rule:MF_03119}, 5.3.1.23 {ECO:0000255|HAMAP-Rule:MF_03119}, Mediator of RhoA-dependent invasion, S-methyl-5-thioribose-1-phosphate isomerase {ECO:0000255|HAMAP-Rule:MF_03119}, Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein {ECO:0000255|HAMAP-Rule:MF_03119}, MRI1 {ECO:0000255|HAMAP-Rule:MF_03119}, MRDI

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) . Independently from catalytic activity, promotes cell invasion in response to constitutive RhoA activation by promoting FAK tyrosine phosphorylation and stress fiber turnover.