MRPL11 polyclonal Antibody | BS61531

MRPL11 polyclonal Antibody | BS61531 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB

Application Range: WB: 1:500~1:1000

Background: Mitochondria have their own translation machinery for production of thirteen proteins that are required for oxidative phosphorylation. MRP-L11 (39S ribosomal protein L11, mitochondrial), also known as CGI-113, is a 192 amino acid protein that is a component of the large ribosomal subunit of the mitochondria. MRP-L11 is one of the 70 protein components of mitochondrial ribosomes that are encoded by the nuclear genome. The gene encoding MRP-L11 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: MRPL11 polyclonal Antibody detects endogenous levels of MRPL11 protein.

Molecular Weight: ~ 20 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: 39S ribosomal protein L11, mitochondrial; L11mt; MRP-L11

Immunogen: Synthetic peptide, corresponding to amino acids 28-72 of Human MRPL11.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 96% (by SDS-PAGE) .

Pathway: