MRPL41 polyclonal Antibody | BS62309

MRPL41 polyclonal Antibody | BS62309 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB IHC

Application Range: WB: 1:500~1:1000 IHC: 1:50~1:200

Background: Mitochondrial ribosomes consist of a large 39S subunit and a small 28S subunit, both of which are comprised of multiple mitochondrial ribosomal proteins (MRPs) that are encoded by nuclear genes and are essential for protein synthesis within mitochondria. MRP-L41 (mitochondrial ribosomal protein L41), also known as cell proliferation-inducing gene 3 protein and BMRP (Bcl-2-interacting mitochondrial ribosomal protein L41), is a 137 amino acid protein that localizes to the mitochondrion, where it exists as a component of the 39S ribosomal subunit and works in conjunction with other MRPs to mediate protein synthesis. Expressed in liver, testis, kidney and thymus, MRP-L41 is in-volved in the cell cycle and apoptosis. Possibly by stabilizing p21 and p27, MRP-L41 has the ability to arrest the cell cycle in the G1 phase. MRP-L41 also enhances p53 stability, therefore contributing to p53-induced apoptosis in response to growth-inhibitory conditions

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: MRPL41 polyclonal Antibody detects endogenous levels of MRPL41 protein.

Molecular Weight: ~ 15 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: 39S ribosomal protein L41, mitochondrial; L41mt; MRP-L41; 39S ribosomal protein L27 homolog; Bcl-2-interacting mitochondrial ribosomal protein L41; Cell proliferation-inducing gene 3 protein; MRP-L27 homolog; Mitochondrial large ribosomal subunit protein mL41; MRPL41; BMRP; MRPL27; RPML27; PIG3

Immunogen: Synthetic peptide, corresponding to Human MRPL41.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: