MRPS14 Antibody | 16-076

MRPS14 Antibody | 16-076 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-128 of human MRPS14 (NP_071383.1) .

Research Area: Other

Tested Application: WB

Application: WB: 1:200 - 1:2000

Specificiy: N/A

Positive Control 1: BxPC-3

Positive Control 2: U-251MG

Positive Control 3: Mouse heart

Positive Control 4: Mouse kidney

Positive Control 5: Mouse liver

Positive Control 6: N/A

Molecular Weight: Observed: 15-17kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: COXPD38, DJ262D12.2, HSMRPS14, MRP-S14, S14mt, 28S ribosomal protein S14, mitochondrial, mitochondrial 28S ribosomal protein S14, mitochondrial small ribosomal subunit protein uS14m

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S14P family. Alternative splicing results in multiple transcript variants.