MSH2 Antibody | 29-555

MSH2 Antibody | 29-555 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Dog, Zebrafish

Homology: N/A

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MSH2.

Research Area: Cell Cycle, Cancer, Apoptosis

Tested Application: E, WB

Application: MSH2 antibody can be used for detection of MSH2 by ELISA at 1:62500. MSH2 antibody can be used for detection of MSH2 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50, 000 - 100, 000.

Specificiy: N/A

Positive Control 1: Cat. No. 1211 - HepG2 Cell Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: 64 kDa, 105 kDa

Validation: N/A

Isoform: N/A

Purification: Antibody is purified by protein A chromatography method.

Clonality: Polyclonal

Clone: N/A

Isotype: N/A

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Concentration: batch dependent

Storage Condition: For short periods of storage (days) store at 4˚C. For longer periods of storage, store MSH2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Alternate Name: MSH2, FCC1, COCA1, HNPCC, LCFS2, HNPCC1

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: MSH2 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC) . When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC.