MSH2 Polyclonal Antibody | E-AB-60195

MSH2 Polyclonal Antibody | E-AB-60195 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: MSH2, COCA1, FCC1, HNPCC, HNPCC1, LCFS2

Application: WB

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Epigenetics and Nuclear Signaling

Background: This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant fusion protein of human MSH2 (NP_000242.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 97 kDa/104 kDa

Molecular Weight(Observed): 105 kDa