Description
MST1R Antibody | 13-211 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: A synthetic peptide of human MST1R
Research Area: Cell Cycle, Immunology, Signal Transduction
Tested Application: WB
Application: WB: 1:500 - 1:1000
Specificiy: N/A
Positive Control 1: Mouse lung
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: Observed: 145kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, pH7.3.
Concentration: N/A
Storage Condition: Store at 4˚C. Avoid freeze / thaw cycles.
Alternate Name: MST1R, C-met-related tyrosine kinase, CD136, CDw136, CD136 antigen, Friend virus susceptibility 2, Fv2, MSP receptor, p185-Ron, PTK8 protein tyrosine kinase 8, RON, Soluble RON variant 3, Soluble RON variant 1, MST1R variant RON30, Oncogene RON, PTK8, MST1R variant RON62, Protein-tyrosine kinase 8, RON variant E2E3, Soluble RON variant 2, Soluble RON variant 4
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. The mature form of this protein is a heterodimer of disulfide-linked alpha and beta subunits, generated by proteolytic cleavage of a single-chain precursor. The beta subunit undergoes tyrosine phosphorylation upon stimulation by MSP. This protein is expressed on the ciliated epithelia of the mucociliary transport apparatus of the lung, and together with MSP, thought to be involved in host defense. Alternative splicing generates multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing.