Description
MSX-122 is a potent inhibitor of CXCR4 with potential antineoplastic and antiviral activities.MSX-122 binds to the chemokine receptor CXCR4, preventing the binding of stromal derived factor-1 (SDF-1) to the CXCR4 receptor and receptor activation, which may result in decreased tumor cell proliferation and migration
MSX-122 is a potent inhibitor of CXCR4 with potential antineoplastic and antiviral activities.MSX-122 binds to the chemokine receptor CXCR4, preventing the binding of stromal derived factor-1 (SDF-1) to the CXCR4 receptor and receptor activation, which may result in decreased tumor cell proliferation and migration
Alternate Name/Synonyms: N,N'-(1,4-phenylenebis(methylene))bis(pyrimidin-2-amine)
Appearance: White solid
Formulation: N/A
CAS Number: 897657-95-3
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₆H₁₆N₆
Molecular Weight: 292.34
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (~0.2 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent CXCR4 inhibitor
MDL Number: N/A
PubChem CID: 11687907
SMILES: C1=CN=C(N=C1)NCC2=CC=C(C=C2)CNC3=NC=CC=N3
InChi: InChI=1S/C16H16N6/c1-7-17-15(18-8-1)21-11-13-3-5-14(6-4-13)12-22-16-19-9-2-10-20-16/h1-10H,11-12H2,(H,17,18,21)(H,19,20,22)
InChi Key: PXZXYRKDDXKDTK-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |