MTERFD1 monoclonal Antibody | MB9372

MTERFD1 monoclonal Antibody | MB9372 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Mouse

Application: WB IHC ICC

Application Range: WB:1:1,000-1:2,000 IHC:1:50-1:200 ICC:1:50

Background: MTERFD1 belongs to the MTERF family which consists of four members including MTERF1, MTERF2, MTERF3 and MTERF4. Previous research showed that MTERFD1 is a mitochondrial protein that interacts with the mitochondrial DNA promoter region and decreases transcription initiation in mammalian mitochondria. This negative regulation is likely important for fine-tuning mitochondria transcription in response to physiological demands. Human mitochondrial transcription termination factor domain 1 (MTERFD1) was mutated in many types of cancer. In vivo and in vitro data indicated that MTERFD1 gene possesses oncogenic properties.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: MTERFD1 monoclonal Antibody detects endogenous levels of MTERFD1 protein.

Molecular Weight: 48/38 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: mTERF3, MTERF3, MTERFD1, CGI-12, CGI 12, mitochondrial, Mitochondrial transcription termination factor 3, MTER1, MTERF domain containing 1, mTERF domain containing protein 1 mitochondrial, mTERF domain-containing protein 1, mTERF3, Mterfd1, Transcription termination factor 3, mitochondrial,

Immunogen: Recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: