MTHFR monoclonal Antibody | MB64078

MTHFR monoclonal Antibody | MB64078 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Mouse, Rat

Application: WB

Application Range: WB 1:500

Background: The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency. [provided by RefSeq, Oct 2009]

Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: methylenetetrahydrofolate reductase (NAD (P) H)

Molecular Weight: 74.4 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: 5,10-methylenetetrahydrofolate reductase (NADPH) ; methylenetetrahydrofolate reductase intermediate form; OTTHUMP00000002367; OTTHUMP00000002368

Immunogen: Human recombinant protein fragment corresponding to amino acids 1-230 of human MTHFR (NP_005948) produced in E.coli.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A