Description
MTNR1A Polyclonal Antibody | E-AB-12579 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: Mel 1A R, MEL-1A-R, Mel1a melatonin receptor, Mel1a receptor, Melatonin receptor 1A, Melatonin receptor type 1A, MelR, MR, MT 1, MT1, MTNR 1A, MTNR1A, MTR1A
Application: WB, IHC, ELISA
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Metabolism, Neuroscience
Background: This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin.
Concentration: 0.4 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthetic peptide of human MTNR1A
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: WB 1:1000-1:5000, IHC 1:25-1:100
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 39 kDa
Molecular Weight(Observed): N/A