MTX-211 | B1968

MTX-211 is a dual inhibitor of EGFR and PI3K. Potentially useful for treatment of KRAS mutant colorectal cancer.

MTX-211 is a dual inhibitor of EGFR and PI3K. Potentially useful for treatment of KRAS mutant colorectal cancer.

B1968 | MTX-211 DataSheet

Alternate Name/Synonyms: N-[2-chloro-5-[4-(3-chloro-4-fluoroanilino)quinazolin-6-yl]pyridin-3-yl]methanesulfonamide

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 1952236-05-3

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₀H₁₄Cl₂FN₅O₂S

Molecular Weight: 478.33

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A dual inhibitor of EGFR and PI3K

MDL Number: N/A

PubChem CID: 121416213

SMILES: CS(=O)(=O)NC1=C(N=CC(=C1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)F)Cl)Cl

InChi: InChI=1S/C20H14Cl2FN5O2S/c1-31(29,30)28-18-7-12(9-24-19(18)22)11-2-5-17-14(6-11)20(26-10-25-17)27-13-3-4-16(23)15(21)8-13/h2-10,28H,1H3,(H,25,26,27)

InChi Key: GUYKCXXNIKKSBC-UHFFFAOYSA-N