Description
MTX-211 is a dual inhibitor of EGFR and PI3K. Potentially useful for treatment of KRAS mutant colorectal cancer.
MTX-211 is a dual inhibitor of EGFR and PI3K. Potentially useful for treatment of KRAS mutant colorectal cancer.
Alternate Name/Synonyms: N-[2-chloro-5-[4-(3-chloro-4-fluoroanilino)quinazolin-6-yl]pyridin-3-yl]methanesulfonamide
Appearance: Crystalline solid
Formulation: N/A
CAS Number: 1952236-05-3
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₀H₁₄Cl₂FN₅O₂S
Molecular Weight: 478.33
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A dual inhibitor of EGFR and PI3K
MDL Number: N/A
PubChem CID: 121416213
SMILES: CS(=O)(=O)NC1=C(N=CC(=C1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)F)Cl)Cl
InChi: InChI=1S/C20H14Cl2FN5O2S/c1-31(29,30)28-18-7-12(9-24-19(18)22)11-2-5-17-14(6-11)20(26-10-25-17)27-13-3-4-16(23)15(21)8-13/h2-10,28H,1H3,(H,25,26,27)
InChi Key: GUYKCXXNIKKSBC-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |