MuERVL-Gag polyclonal Antibody | BS90896

MuERVL-Gag polyclonal Antibody | BS90896 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Mouse

Application: ICC

Application Range: ICC:1:200

Background: A large number of retrotransposons are expressed when the zygotic genome is first transcribed, including the endogenous retroviruses (ERVs), LINE-1 elements, and the non-autonomous SINE elements. At the 2C stage, MuERV-L/MERVL retrovirus-like elements are transiently de-repressed and produce 3% of the transcribed mRNAs. Following the 2C stage, MERVL-retroelement expression is silenced. The newly study discovered that this regulated pattern of MERVL expression overlapped with greater than one hundred 2C-specific genes that have co-opted regulatory elements from these foreign retroviruses to initiate their transcription.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: MuERVL-Gag polyclonal Antibody detects endogenous levels of MuERVL-Gag protein.

Molecular Weight: 67 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Gag,

Immunogen: peptide

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Peptide affinity purified

Pathway: