Musashi 1 polyclonal Antibody | BS90897

Musashi 1 polyclonal Antibody | BS90897 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB ICC/IF IHC IP FC

Application Range: WB:1:1000 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:200

Background: Musashi1 (Msi1) is an RNA-binding protein expressed in neural progenitor cells and neural stem cells. Msi1 is the mammalian homolog of Drosophila Musashi. The gene encoding human Msi1 encodes a 362 amino acid protein. In murine embryonic neural progenitor cells, Msi1 localizes to the cytoplasm and is downregulated during differentiation. Msi1 binds to NUMB, which encodes a membrane-associated antagonist of Notch signaling. Msi1 appears to function in the proliferation and maintenance of stem cell populations of the central nervous system. In addition to its usefulness as a marker for neural progenitor cells in normal human brains, Msi1 is also a marker for human gliomas. In rats, Msi1 is expressed in Sertoli cells of the testis and granulosa cells of the ovary.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: Musashi 1 polyclonal Antibody detects endogenous levels of Musashi 1 protein.

Molecular Weight: 39 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: LRP-1, A2MR, APOER, CD91, LRP1, Msi 1, Msi1, MSI1H, Musashi homolog 1, Musashi-1, Musashi1, RNA binding protein Musashi homolog 1, RNA-binding protein Musashi homolog 1,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: