Description
MUT Antibody | 19-232 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 451-750 of human MUT (NP_000246.2) .
Research Area: Cancer, Signal Transduction
Tested Application: WB
Application: WB: 1:1000 - 1:2000
Specificiy: N/A
Positive Control 1: LO2
Positive Control 2: HeLa
Positive Control 3: BT-474
Positive Control 4: 22Rv1
Positive Control 5: Mouse liver
Positive Control 6: Mouse kidney
Molecular Weight: Observed: 83kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: MCM, MUT, methylmalonyl-CoA mutase, mitochondrial, methylmalonyl Coenzyme A mutase, methylmalonyl-CoA isomerase, methylmalonyl-CoA mutase c.*192delA, methylmalonyl-CoA mutase c.*51C>G, methylmalonyl-CoA mutase variant c.1495G>A, methylmalonyl-CoA mutase variant c.2011A>G, methylmalonyl-CoA mutase variant c.2150G>T, methylmalonyl-CoA mutase variant c.322C>T, methylmalonyl-CoA mutase variant c.613_615delGAA, methylmalonyl-CoA mutase variant c.636G>A, methylmalonyl-CoA mutase variant c.643G>A, mutant methylmalonyl CoA mutase, truncated methylmalonyl CoA mutase, truncated methylmalonyl-CoA mutase variant c.1420C>T, truncated methylmalonyl-CoA mutase variant c.2179C>T, truncated methylmalonyl-CoA mutase variant c.91C>T
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene encodes the mitochondrial enzyme methylmalonyl Coenzyme A mutase. In humans, the product of this gene is a vitamin B12-dependent enzyme which catalyzes the isomerization of methylmalonyl-CoA to succinyl-CoA, while in other species this enzyme may have different functions. Mutations in this gene may lead to various types of methylmalonic aciduria.