MUTYH Polyclonal Antibody | E-AB-10477

MUTYH Polyclonal Antibody | E-AB-10477 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: A/G specific adenine DNA glycosylase, A/G-specific adenine DNA glycosylase, Adenine DNA glycosylase, CYP2C, hMYH, MGC4416, MutY (E. coli) homolog, MutY homolog (E. coli), MutY homolog, MutY, E. coli, homolog of, Mutyh, MUTYH, MYH, rMYH

Application: WB, IHC, ELISA

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Epigenetics and Nuclear Signaling

Background: This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7, 8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Concentration: 0.3 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein of human MUTYH

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:1000-1:5000, IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 60 kDa

Molecular Weight(Observed): N/A