MYBBP1A Antibody [AMM02562G]

MYBBP1A Antibody [AMM02562G] | Gentaur UK, US & Europe Distribution

Product Category: Monoclonal Antibodies

Host: Mouse

Species Reactivity: H

Specificity: This MYBBP1A antibody is generated from a mouse immunized with a recombinant protein between 1104-1328 amino acids from human MYBBP1A.

Cellular Localisation: Cytoplasm. Nucleus. Nucleus, nucleolus. Note=Shuttles between the nucleus and cytoplasm. Nuclear import may be mediated by KPNA2, while export appears to depend partially on XPO1/CRM1 (By similarity) . Predominantly nucleolar. {ECO:0000250|UniProtKB:Q7TPV4}

Molecular Weight: 148855

Clone: Monoclonal

Gene Name: MYBBP1A

Gene ID: 10514

Function: May activate or repress transcription via interactions with sequence specific DNA-binding proteins (By similarity) . Repression may be mediated at least in part by histone deacetylase activity (HDAC activity) (By similarity) . Acts as a corepressor and in concert with CRY1, represses the transcription of the core circadian clock component PER2 (By similarity) . Preferentially binds to dimethylated histone H3 'Lys-9' (H3K9me2) on the PER2 promoter (By similarity) . Has a role in rRNA biogenesis together with PWP1 (PubMed:29065309) .

Summary: N/A

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:5000

Synonyms: Myb-binding protein 1A, MYBBP1A, P160