MYBPC1 Antibody | 5649

MYBPC1 Antibody | 5649 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Homology: N/A

Immunogen: MYBPC1 antibody was raised against a 12 amino acid synthetic peptide near the carboxy terminus of human MYBPC1.
The immunogen is located within the last 50 amino acids of MYBPC1.

Research Area: Homeostasis

Tested Application: E, IHC-P

Application: MYBPC1 antibody can be used for detection of MYBPC1 by immunohistochemistry at 5 μg/mL. For immunofluorescence start at 5 μg/mL.
Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested.

Specificiy: N/A

Positive Control 1: Cat. No. 1375 - Human Skeletal Muscle Tissue Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: MYBPC1 Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: MYBPC1 Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: MYBPC1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: MYBPC1 Antibody: LCCS4, MYBPCC, MYBPCS, Myosin-binding protein C, slow-type, C-protein, skeletal muscle slow isoform, Slow MyBP-C

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: MYBPC1 Antibody: Myosin binding protein C (MYBPC) is a component of the thick filament of striated muscle, with the slow-type isoform designated MYBPC1. Both the fast-type (MYBPC2) and slow-type MYBPC protein contains seven immunoglobulin C2 motifs and three fibronectin type-III repeats. Multiple isoforms of MYBPC1 are known to exist, and are present in varying amounts in different skeletal muscles. It is thought that the MYBPC1 slow subfamily may play important roles in the assembly and stabilization of sarcomeric M- and A-bands and regulate the contractile properties of the actomyosin filaments.