MYBPC3 polyclonal Antibody | BS71538

MYBPC3 polyclonal Antibody | BS71538 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Rat

Application: WB,IHC

Application Range: WB 1:2000 - 1:5000 IHC 1:50 - 1:200

Background: MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: MYBPC3 polyclonal Antibody detects endogenous levels of MYBPC3 protein.

Molecular Weight: ~ 170 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: FHC; CMH4; CMD1MM; LVNC10; MYBP-C

Immunogen: Recombinant protein of human MYBPC3

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: