MYC Antibody [AMM02578G]

MYC Antibody [AMM02578G] | Gentaur UK, US & Europe Distribution

Product Category: Monoclonal Antibodies

Host: Mouse

Species Reactivity: H

Specificity: This MYC antibody is generated from a mouse immunized with a recombinant protein of human MYC Isform 2.

Cellular Localisation: Nucleus, nucleoplasm. Nucleus, nucleolus

Molecular Weight: 48804

Clone: Monoclonal

Gene Name: MYC

Gene ID: 4609

Function: Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3' (PubMed:24940000, PubMed:25956029) . Activates the transcription of growth-related genes (PubMed:24940000, PubMed:25956029) . Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis (PubMed:24940000, PubMed:25956029) . Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells (By similarity) . Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity) .

Summary: N/A

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:2000

Synonyms: Myc proto-oncogene protein, Class E basic helix-loop-helix protein 39, bHLHe39, Proto-oncogene c-Myc, Transcription factor p64, MYC, BHLHE39