MYH2 Antibody | 15-967

MYH2 Antibody | 15-967 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 550-650 of human MYH2 (NP_001093582.1) .

Research Area: Other

Tested Application: WB, IHC, IF

Application: WB: 1:200 - 1:2000
IHC: 1:50 - 1:200
IF: 1:50 - 1:200

Specificiy: N/A

Positive Control 1: Mouse skeletal muscle

Positive Control 2: Rat skeletal muscle

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Observed: 223kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: IBM3A, MYHSA2, MYHas8, MYPOP, MyHC-2A, MyHC-IIa, MYH2, myosin-2, fast 2a myosin heavy chain, inclusion body myopathy 3, autosomal dominant, myosin heavy chain 2a, myosin heavy chain IIa, myosin heavy chain, skeletal muscle, adult 2, myosin, heavy chain 2, skeletal muscle, adult, myosin, heavy polypeptide 2, skeletal muscle, adult, type IIA myosin heavy chain

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: Myosins are actin-based motor proteins that function in the generation of mechanical force in eukaryotic cells. Muscle myosins are heterohexamers composed of 2 myosin heavy chains and 2 pairs of nonidentical myosin light chains. This gene encodes a member of the class II or conventional myosin heavy chains, and functions in skeletal muscle contraction. This gene is found in a cluster of myosin heavy chain genes on chromosome 17. A mutation in this gene results in inclusion body myopathy-3. Multiple alternatively spliced variants, encoding the same protein, have been identified.