Description
MYO6 Polyclonal Antibody | E-AB-65994 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: MYO6, DFNA22, DFNB37, Myo6-007, Myo6-008, myosin VI
Application: WB, IF
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Signal Transduction
Background: This gene encodes a reverse-direction motor protein that moves toward the minus end of actin filaments and plays a role in intracellular vesicle and organelle transport. The protein consists of a motor domain containing an ATP- and an actin-binding site and a globular tail which interacts with other proteins. This protein maintains the structural integrity of inner ear hair cells and mutations in this gene cause non-syndromic autosomal dominant and recessive hearing loss. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant fusion protein of human MYO6 (NP_004990.3).
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000 IF 1:50-1:200
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 145 kDa/146 kDa/148 kDa/149 kDa
Molecular Weight(Observed): 150 kDa