MYO7A Polyclonal Antibody | E-AB-13433

MYO7A Polyclonal Antibody | E-AB-13433 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Deafness autosomal dominant 11, Deafness autosomal recessive 2, DFNA11, DFNB 2, DFNB2, Myo7a, Myosin 7a, Myosin VIIA (Usher syndrome 1B (autosomal recessive, severe)), Myosin VIIa, Myosin, unconventional, family VII, member A, MYOVIIA, MYU7A, NSRD 2, NSRD2, Unconventional myosin VIIa, Ush 1B, Ush1b, Usher syndrome 1B

Application: IHC, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Signal Transduction

Background: This gene is a member of the myosin gene family. Myosins are mechanochemical proteins characterized by the presence of a motor domain, an actin-binding domain, a neck domain that interacts with other proteins, and a tail domain that serves as an anchor. This gene encodes an unconventional myosin with a very short tail. Defects in this gene are associated with the mouse shaker-1 phenotype and the human Usher syndrome 1B which are characterized by deafness, reduced vestibular function, and (in human) retinal degeneration. Alternative splicing results in multiple transcript variants.

Concentration: 0.5 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human MYO7A

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:25-1:100

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A