Description
MYOF Polyclonal Antibody | E-AB-65311 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: MYOF, FER1L3, myoferlin
Application: WB
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Cell Biology, Cardiovascular
Background: Mutations in dysferlin, a protein associated with the plasma membrane, can cause muscle weakness that affects both proximal and distal muscles. The protein encoded by this gene is a type II membrane protein that is structurally similar to dysferlin. It is a member of the ferlin family and associates with both plasma and nuclear membranes. The protein contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. Two transcript variants encoding different isoforms have been found for this gene. Other possible variants have been detected, but their full-length nature has not been determined.
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant fusion protein of human MYOF (NP_038479.1).
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification Method: Affinity purification
Dilution: WB 1:200-1:2000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 17 kDa/46 kDa/49 kDa/179 kDa/229 kDa/233 kDa/234 kDa
Molecular Weight(Observed): 250 kDa