Myosin VIIa polyclonal Antibody | BS60184

Myosin VIIa polyclonal Antibody | BS60184 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB

Application Range: WB: 1:500~1:1000

Background: Myosins are molecular motors that move along filamentous Actin and influence cellular movements such as phagocytosis. There are seven classes of myosins in vertebrates, including Myosin II, and six unconventional Myosin classes, designated I, V, VI, VII, IX and X. Myosin VIIa is a plus end-directed motor that influences cilia formation and cell adhesion. Mutations in the human Myosin VIIa gene correlate with Usher syndrome, a disease characterized by congenital sensorineural deafness, vestibular dysfunction and retinitis pigmentosa.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Myosin VIIa polyclonal Antibody detects endogenous levels of Myosin VIIa protein.

Molecular Weight: ~ 254 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Unconventional myosin-VIIa; MYO7A; USH1B

Immunogen: A synthetic peptide corresponding to residues in Human Myosin VIIa.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: