MYST4 | histone acetyltransferase KAT6B | AS05 078

MYST4 | histone acetyltransferase KAT6B | AS05 078 | Gentaur UK, US & Europe Distribution

Immunogen: KLH-conjugated synthetic peptide chosen from a bovine histone acetyltrasferase MYST4 A7E390

Host: Rabbit

Conjugation: N/A

Clonality: Polyclonal

Isotype: N/A

Purity: Immunogen affinity purified serum in PBS pH 7.4.

Format: Lyophilized

Tested Application: Imunohistochemistry (IHC) Immunoprecipitation (IP), Western blot (WB)

Related Products: Secondary antibodies

Recommended Dilutions: 1 : 1000 (IHC), 1 :7500 (WB)

Molecular weight: 230 kDa

Confirmed Reactivity: bovine, antibody will also react with bovine MYST4 isoforms (MORF and MORF)

Predicted Reactivity: Black flying fox, Human (isoform 2, 3), Mouse (isoform 2, 3, 4), Vampire bat

Not reactive in: Plants

Additional Information: Blocking used in IHC was done with 5% dry milk, Secondary antibodyused: Fluorescein-conjugated goat anti-rabbit IgG (Molecular Probes) diluted 1:1000

Background: MYST4 (KAT6B), EC=2.3.1.48, is a transcriptional coactivator with histone acetyltransferase activity. This protein is essential for normal mouse embryo development. Mouse mutants for MYST4 show craniofacial abnormalities, retards in post-natal development, defaults in the nervous system and neurogenique problems. Abnormal chromosomic rearengements of MYST4 with the CBP gene is involved in acute myeloid leukaemia (AML) -M4. Furthermore, in the ovary and the testis of mammals, MYST4 is mainly localized in specialized cells involved in male and female gametogenesis. Alternative names: Histone acetyltransferase MOZ2, MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4, Monocytic leukemia zinc finger protein-related factor.

Reconstitution: For reconstitution add 125 µl of sterile water

Storage: Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.

TAIR Nnumbre: N/A

Category: Other proteins

Research Area: Cell Biology