N Cadherin Antibody, KO Validated | 18-917

N Cadherin Antibody, KO Validated | 18-917 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 750-850 of human N Cadherin (NP_001783.2) .

Research Area: Cancer, Cell Cycle, Immunology, Signal Transduction, Stem Cell

Tested Application: WB, IP

Application: WB: 1:500 - 1:1000
IP: 1:50 - 1:100

Specificiy: N/A

Positive Control 1: HeLa

Positive Control 2: A-549

Positive Control 3: 293T

Positive Control 4: Mouse liver

Positive Control 5: Mouse brain

Positive Control 6: Mouse heart

Molecular Weight: Observed: 135kDa

Validation: Antibody is Knockout validated.

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: CDH2, CDw325, CDHN, Cadherin-2, CD325, CD325 antigen, N Cadherin, N-cadherin, NCAD, Neural cadherin, N-cadherin 1, Neural-cadherin

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes a classical cadherin and member of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein is proteolytically processed to generate a calcium-dependent cell adhesion molecule and glycoprotein. This protein plays a role in the establishment of left-right asymmetry, development of the nervous system and the formation of cartilage and bone.