N6-Methyladenosine | B2715

N6-Methyladenosine is an adenosine analog that inhibits epinephrine-induced contraction of isolated guinea pig ileum and thoracic aorta. It decreases arterial blood pressure and renal blood flow and increases peripheral resistance in anesthetized dogs. As a modification in the messenger RNA (mRNA), it is the most prevalent internal modification of mRNA in all higher eukaryotes. Also found in tRNA, rRNA, and small nuclear RNA (snRNA).

N6-Methyladenosine is an adenosine analog that inhibits epinephrine-induced contraction of isolated guinea pig ileum and thoracic aorta. It decreases arterial blood pressure and renal blood flow and increases peripheral resistance in anesthetized dogs. As a modification in the messenger RNA (mRNA), it is the most prevalent internal modification of mRNA in all higher eukaryotes. Also found in tRNA, rRNA, and small nuclear RNA (snRNA).

B2715 | N6-Methyladenosine DataSheet

Alternate Name/Synonyms: NSC-29409,N-methyl-adenosine,m6A,NSC29409

Appearance: White to off-white solid

Formulation:

CAS Number: 1867-73-8

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₁H₁₅N₅O₄

Molecular Weight: 281.27

Cell-Permeable?: TRUE

Purity: ≥98% by HPLC

Solubilities: ~10 mg/ml DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: An adenosine analog

MDL Number: MFCD00005739

PubChem CID: 102175

SMILES: [H][C@]1(O[C@H](CO)[C@@H](O)[C@H]1O)N2C=NC3=C(NC)N=CN=C32

InChi: InChI=1S/C11H15N5O4/c1-12-9-6-10(14-3-13-9)16(4-15-6)11-8(19)7(18)5(2-17)20-11/h3-5,7-8,11,17-19H,2H2,1H3,(H,12,13,14)/t5-,7-,8-,11-/m1/s1

InChi Key: VQAYFKKCNSOZKM-IOSLPCCCSA-N