NAA40 Antibody (C-Term) [ApR05001G]

NAA40 Antibody (C-Term) [ApR05001G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M

Specificity: This NAA40 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 179-222 amino acids from the human region of human NAA40.

Cellular Localisation: Cytoplasm. Nucleus

Molecular Weight: 27194

Clone: Polyclonal

Gene Name: NAA40 {ECO:0000303|PubMed:19660095, ECO:0000312|HGNC:HGNC:25845}

Gene ID: 79829

Function: N-alpha-acetyltransferase that specifically mediates the acetylation of the N-terminal residues of histones H4 and H2A (PubMed:21935442, PubMed:25619998) . In contrast to other N-alpha- acetyltransferase, has a very specific selectivity for histones H4 and H2A N-terminus and specifically recognizes the 'Ser-Gly-Arg-Gly sequence' (PubMed:21935442, PubMed:25619998) . Acts as a negative regulator of apoptosis (PubMed:26666750) . May play a role in hepatic lipid metabolism (By similarity) .

Summary: Tissue Location: Widely expressed; with the highest expression level in liver and the lowest expression in brain (at protein level)

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:2000

Synonyms: N-alpha-acetyltransferase 40, 2.3.1.-, N-acetyltransferase 11, NatD catalytic subunit, NAA40, NAT11