NAALDase Inhibitor, PMPA | 2478

PMPA is a highly potent and selective inhibitor of NAALADase (N-acetylated-alpha-linked-acidic dipeptidase or glutamate carboxypeptidase II or GCPII) with a Ki value of 275 pM. Displays robust neuroprotective activity in both in vitro and in vivo models of ischemia.

PMPA is a highly potent and selective inhibitor of NAALADase (N-acetylated-alpha-linked-acidic dipeptidase or glutamate carboxypeptidase II or GCPII) with a Ki value of 275 pM. Displays robust neuroprotective activity in both in vitro and in vivo models of ischemia.

2478 | NAALDase Inhibitor, PMPA DataSheet

Alternate Name/Synonyms: 2-(Phosphonomethyl)pentane-1,5-dioi​c acid; PMPA

Appearance: White solid

Formulation: N/A

CAS Number: 173039-10-6

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: N/A

Molecular Formula: C₆H₁₁O₇P

Molecular Weight: 226.12

Cell-Permeable?: Yes

Purity: ≥95% by NMR

Solubilities: H₂O (>20 mg/ml)

Handling: Protect from moisture

Country of Origin: USA

Tag Line: A potent NAALADase inhibitor

MDL Number: N/A

PubChem CID: 10130754

SMILES: C(CC(=O)O)C(CP(=O)(O)O)C(=O)O

InChi: InChI=1S/C6H11O7P/c7-5(8)2-1-4(6(9)10)3-14(11,12)13/h4H,1-3H2,(H,7,8)(H,9,10)(H2,11,12,13)

InChi Key: ISEYJGQFXSTPMQ-UHFFFAOYSA-N