Nampt-IN-1 | B1171

Nampt-IN-1 is a potent and selective NAMPT (Nicotinamide phosphoribosyltransferase) inhibitor. Displays potent anticancer properties. NAMPT is found to be upregulated in various cancer cells and inhibition of NAMPT leads to depletion of NAD+ which leads to low levels of ATP resulting in attenuation of proliferating cancer cells.

Nampt-IN-1 is a potent and selective NAMPT (Nicotinamide phosphoribosyltransferase) inhibitor. Displays potent anticancer properties. NAMPT is found to be upregulated in various cancer cells and inhibition of NAMPT leads to depletion of NAD+ which leads to low levels of ATP resulting in attenuation of proliferating cancer cells.

B1171 | Nampt-IN-1 DataSheet

Alternate Name/Synonyms: 2-Hydroxy-2-methyl-N-[1,2,3,4-tetrahydro-2-[2-(3-pyridinyloxy)acetyl]-6-isoquinolinyl]-1-propanesulfonamide

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 1698878-14-6

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₀H₂₅N₃O₅S

Molecular Weight: 419.49

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent and selective NAMPT (Nicotinamide phosphoribosyltransferase) inhibitor

MDL Number: N/A

PubChem CID: 92044379

SMILES: CC(C)(CS(=O)(=O)NC1=CC2=C(CN(CC2)C(=O)COC3=CN=CC=C3)C=C1)O

InChi: InChI=1S/C20H25N3O5S/c1-20(2,25)14-29(26,27)22-17-6-5-16-12-23(9-7-15(16)10-17)19(24)13-28-18-4-3-8-21-11-18/h3-6,8,10-11,22,25H,7,9,12-14H2,1-2H3

InChi Key: QHHSCLARESIWBH-UHFFFAOYSA-N