NAT8L Antibody (N-Term) [APR33396G]

NAT8L Antibody (N-Term) [APR33396G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This NAT8L antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 59-93 amino acids from human NAT8L.

Cellular Localisation: Cytoplasm. Membrane; Single-pass membrane protein. Microsome membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein. Rough endoplasmic reticulum membrane; Single-pass membrane protein. Note=Its enzymatic activity contribution is quantitatively larger in mitochondrial compartment than in extramitochondrial compartment

Molecular Weight: 32837

Clone: Polyclonal

Gene Name: NAT8L

Gene ID: 339983

Function: Plays a role in the regulation of lipogenesis by producing N- acetylaspartate acid (NAA), a brain-specific metabolite. NAA occurs in high concentration in brain and its hydrolysis plays a significant part in the maintenance of intact white matter. Promotes dopamine uptake by regulating TNF-alpha expression. Attenuates methamphetamine-induced inhibition of dopamine uptake.

Summary: Tissue Location: Expressed in brain..

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: IHC-P-Leica, WB

Dilution: IHC-P-Leica--1:250 WB--1:1000

Synonyms: N-acetylaspartate synthetase, NAA synthetase, 2.3.1.17, Camello-like protein 3, N-acetyltransferase 8-like protein, NAT8L, CML3