NCGC00244536 | B1956

NCGC00244536 is a potent KDM4A inhibitor (IC₅₀ = 10 nM). NCGC00244536 displays high selectivity for the fast-growing AR-negative PC3 cells (IC₅₀ = 40 nM) and over 100-fold selectivity against the immortalized prostate epithelial cell lines PrEC1 and PrEC4. Displays anticancer activity.

NCGC00244536 is a potent KDM4A inhibitor (IC₅₀ = 10 nM). NCGC00244536 displays high selectivity for the fast-growing AR-negative PC3 cells (IC₅₀ = 40 nM) and over 100-fold selectivity against the immortalized prostate epithelial cell lines PrEC1 and PrEC4. Displays anticancer activity.

B1956 | NCGC00244536 DataSheet

Alternate Name/Synonyms: 3-(8-hydroxyquinolin-6-yl)-N-(3-phenylpropyl)benzamide

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 2003260-55-5

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₅H₂₂N₂O₂

Molecular Weight: 382.46

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent KDM4A inhibitor

MDL Number: N/A

PubChem CID: 127030711

SMILES: C1=CC=C(C=C1)CCCNC(=O)C2=CC=CC(=C2)C3=CC(=C4C(=C3)C=CC=N4)O

InChi: InChI=1S/C25H22N2O2/c28-23-17-22(16-20-12-6-13-26-24(20)23)19-10-4-11-21(15-19)25(29)27-14-5-9-18-7-2-1-3-8-18/h1-4,6-8,10-13,15-17,28H,5,9,14H2,(H,27,29)

InChi Key: NYKBXXGHEMXSBB-UHFFFAOYSA-N