ND3 polyclonal Antibody | BS1406

ND3 polyclonal Antibody | BS1406 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Mouse

Application: WB

Application Range: WB: 1:500~1:1000 IHC: 1:50~1:200

Background: NADH:ubiquinone oxidoreductase (complex I) is an extremely complicated multiprotein complex located in the inner mitochondrial membrane. Human complex I is important for energy metabolism because its main function is to transport electrons from NADH to ubiquinone, which is accompanied by trans-location of protons from the mitochondrial matrix to the intermembrane space. Human complex I appears to consist of 41 subunits. A small number of complex I subunits are the products of mitochondrial genes (subunits 1-7), while the remainder are nuclear encoded and imported from the cytoplasm. NADH dehydrogenase subunit 3 (ND3) localizes to the hydrophobic protein fragment of complex I. Mutations in the gene encodiing for ND3 may be associated with Parkinson disease.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: ND3 polyclonal Antibody detects endogenous levels of ND3 protein.

Molecular Weight: ~ 13 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: NADH-ubiquinone oxidoreductase chain 3 (EC:1.6.5.3) ; NADH dehydrogenase subunit 3; Mtnd3; mt-Nd3; Nd3

Immunogen: A synthetic peptide corresponding to amino acids 21-34 of Mouse ND3.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: NF-kB Signaling,PI3K AKT signaling,Immune Cell Signaling,STING Signaling,Inhibition of Apoptosis,Toll-like Receptor signaling,