NDST2 Antibody (C-term) [APR10822G]

NDST2 Antibody (C-term) [APR10822G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M

Specificity: This NDST2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 817-844 amino acids of human NDST2.

Cellular Localisation: Golgi apparatus membrane; Single- pass type II membrane protein

Molecular Weight: 100875

Clone: Polyclonal

Gene Name: NDST2

Gene ID: 8509

Function: Essential bifunctional enzyme that catalyzes both the N- deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in determining the extent and pattern of sulfation of heparan sulfate. Required for the exosomal release of SDCBP, CD63 and syndecan (PubMed:22660413) .

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2, Glucosaminyl N-deacetylase/N-sulfotransferase 2, NDST-2, N-heparan sulfate sulfotransferase 2, N-HSST 2, Heparan sulfate N-deacetylase 2, 3---, Heparan sulfate N-sulfotransferase 2, 282-, NDST2, HSST2