NDUFS1 Antibody | 18-729

NDUFS1 Antibody | 18-729 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 80-290 of human NDUFS1 (NP_004997.4) .

Research Area: Apoptosis, Cancer, Cell Cycle, Neuroscience

Tested Application: WB, IHC

Application: WB: 1:500 - 1:2000
IHC: 1:50 - 1:200

Specificiy: N/A

Positive Control 1: HeLa

Positive Control 2: Raji

Positive Control 3: NCI-H460

Positive Control 4: PC-3

Positive Control 5: 293T

Positive Control 6: HepG2

Molecular Weight: Observed: 79kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: NDUFS1, PRO1304, OTTHUMP00000206345, NADH-coenzyme Q reductase, NADH dehydrogenase (ubiqui) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) , 75kDa, MGC26839, complex I, mitochondrial respirato, CI-75Kd, CI-75k

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The protein encoded by this gene belongs to the complex I 75 kDa subunit family. Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. This protein is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized. Mutations in this gene are associated with complex I deficiency. Several transcript variants encoding different isoforms have been found for this gene.