Description
A necroptosis inhibitor. The biological activity of necrostatin-7 (Nec-7) is different from that of necrostatin-1 to -5 as Nec-7 does not inhibit RIP1 kinase. Nec-7 may target an additional regulatory molecule in the pathway.
Necrostatin-7 is a necroptosis inhibitor. The biological activity of necrostatin-7 (Nec-7) is different from that of necrostatin-1 to -5 as Nec-7 does not inhibit RIP1 kinase. Nec-7 may target an additional regulatory molecule in the pathway.
1866 | Necrostatin-7 DataSheet
Alternate Name/Synonyms: (Z)-5-((3-(4-Fluorophenyl)-1H-pyrazol-4-yl)methylene)-2-imino-3-(thiazol-2-yl)thiazolidin-4-one; Nec-7
Appearance: Yellow solid
Formulation: N/A
CAS Number: 351062-08-3
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₆H₁₀N₅OS₂F
Molecular Weight: 371.41
Cell-Permeable?: Yes
Purity: ≥98% by NMR
Solubilities: DMSO or EtOH
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A necroptosis inhibitor
MDL Number: MFCD02334728
PubChem CID: N/A
SMILES: N/A
InChi: N/A
InChi Key: N/A
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
24 months |