Necrostatin-7 | 1866

A necroptosis inhibitor. The biological activity of necrostatin-7 (Nec-7) is different from that of necrostatin-1 to -5 as Nec-7 does not inhibit RIP1 kinase. Nec-7 may target an additional regulatory molecule in the pathway.

Necrostatin-7 is a necroptosis inhibitor. The biological activity of necrostatin-7 (Nec-7) is different from that of necrostatin-1 to -5 as Nec-7 does not inhibit RIP1 kinase. Nec-7 may target an additional regulatory molecule in the pathway.

1866 | Necrostatin-7 DataSheet

Alternate Name/Synonyms: (Z)-5-((3-(4-Fluorophenyl)-1H-pyrazol-4-yl)methylene)-2-imino-3-(thiazol-2-yl)thiazolidin-4-one; Nec-7

Appearance: Yellow solid

Formulation: N/A

CAS Number: 351062-08-3

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₆H₁₀N₅OS₂F

Molecular Weight: 371.41

Cell-Permeable?: Yes

Purity: ≥98% by NMR

Solubilities: DMSO or EtOH

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A necroptosis inhibitor

MDL Number: MFCD02334728

PubChem CID: N/A

SMILES: N/A

InChi: N/A

InChi Key: N/A