NECTIN1 Polyclonal Antibody | E-AB-15611

NECTIN1 Polyclonal Antibody | E-AB-15611 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: CD111, CD111 antigen, CLPED1, ectodermal dysplasia 4 (Margarita Island type), ED4, Herpes virus entry mediator C, Herpesvirus entry mediator C, Herpesvirus Ig like receptor, Herpesvirus Ig-like receptor, HIgR, HveC, MGC142031, Nectin 1, Nectin-1, OFC7, OROFACIAL CLEFT 7, OTTHUMP00000232093, OTTHUMP00000232094, OTTHUMP00000232095, Poliovirus receptor related protein 1, poliovirus receptor-like 1, Poliovirus receptor-related protein 1, PRR, PRR1, PVRL 1, PVRL1, PVRL1, PVRR, PVRR1, SK-12

Application: WB, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Microbiology, Neuroscience

Background: This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini.

Concentration: 0.3 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human PVRL1

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:200-1:1000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 57 kDa

Molecular Weight(Observed): N/A