Description
NELFE Antibody | 19-008 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human, Mouse
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human NELFE (NP_002895.3) .
Research Area: Other
Tested Application: WB, IHC, IF
Application: WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IF: 1:50 - 1:200
Specificiy: N/A
Positive Control 1: HeLa
Positive Control 2: 293T
Positive Control 3: HepG2
Positive Control 4: SW480
Positive Control 5: Mouse liver
Positive Control 6: Mouse testis
Molecular Weight: Observed: 43kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: D6S45, NELF-E, RD, RDBP, RDP, negative elongation factor E, RD RNA-binding protein, RNA-binding protein RD, major histocompatibility complex gene RD, negative elongation factor polypeptide E, nuclear protein
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: The protein encoded by this gene is part of a complex termed negative elongation factor (NELF) which represses RNA polymerase II transcript elongation. This protein bears similarity to nuclear RNA-binding proteins; however, it has not been demonstrated that this protein binds RNA. The protein contains a tract of alternating basic and acidic residues, largely arginine (R) and aspartic acid (D) . The gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6.