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Neurocan Polyclonal Antibody | BS65654
- SKU:
- BW-BS65654
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- Usually ships in 5 working days
Description
Neurocan Polyclonal Antibody | BS65654 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human,Mouse,Rat,
Application: IHC-P,
Application Range: IHC-P=1:100-500
Background: Neurocan is the major soluble chondroitin sulfate proteoglycan in the brain. It is thought to play a functional role in axonal growth and guidance and in the establishment of specific neural pathways during embryonic brain development. Neurocan expression in the brain is developmentally regulated. Early on the major form of neurocan consists of a 245kD core protein with approximately two chondroitin sulfate glycosoaminoglycan chains of 22kD each. Later neurocan comprises a 180kD core protein Both forms of neurocan contain only chondroitin 4-sulfate glycosoaminoglycan chains. By virtue of their high expression at sites of neural damage and trauma, chondroitin sulfate proteoglycans, including neurocan, are thought to inhibit successful nerve regeneration. Alternative names: Chondroitin sulfate proteoglycan 3; Cspg3; NCAN; NEUR; Neurocan core protein.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: Neurocan Polyclonal Antibody detects endogenous levels of Neurocan protein.
Molecular Weight: 140kD
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Chondroitin sulfate proteoglycan 3; Cspg3; NCAN; NEUR; Neurocan core protein; NCAN_HUMAN.
Immunogen: KLH conjugated synthetic peptide derived from human Neurocan
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: affinity purified by Protein A
Pathway: